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The first randomized, placebo-controlled parallel study
of theaflavins on lipid levels and lipoproteins
of individuals with hypercholesterolemia was
performed by Nashai Biotech LLC in China, PRC.
The hypothesis was that theaflavins not only
significantly lower LDL cholesterol, the “bad
cholesterol”, in adults with high LDL cholesterol,
but is free of side effects. Although further research
is needed to more fully substantiate the effectiveness
of theaflavins, the outcomes of the study substantiated
the hypothesis.
A concentration of theaflavins in pill form
as well as a placebo pill were administered in exactly
the same fashion to separates groups and were tracked
using the same testing and the same indicators. Study
participants that received theaflavins pills compared
to those who took placebos showed 11.3 percent decreased
serum of the total cholesterol and 16.4 percent reduced
LDL-C.
Comparing the two test groups mean percentage change
in the following areas, the theaflavins group’s
mean levels of TC,TG,HDL and LDL changed by 11.3 percent,
2.6 percent, 23 percent, and 16.4 percent respectively.
The placebo group’s mean levels of TC, TG, HDL
and LDL changed by 0.7 percent, 5.6 percent, 0.7 percent,
and 0.26 percent.
Table 2 Mean percent Change (X±SE)
from Baseline in Lipid
Parameters in the study of theaflavins on hypercholesterolemia
| |
4 weeks |
12 weeks |
| |
Theaflavins(n=114) |
Placebo(n=109) |
Theaflavins(n=114) |
Placebo(n=106) |
| TC(%) |
-6.70±84 |
0.05±87 |
-11.34±89 |
-0.72±77 |
| LDL-c (%) |
-9.58±09 |
1.75±29 |
-16.40±10 |
0.26±24 |
| HDL-c (%) |
0.35±10 |
-0.36±65 |
2.30±06 |
-0.69±59 |
| TG (%) |
0.51±58 |
11.79±82 |
2.58±52 |
5.58±76 |
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Other recent observations indicate that intragastric
administration of black tea inhibits plate aggregation
and prevents experimental coronary thrombosis in
dogs, hence proving further indication that Black
Tea prevents cardiovascular diseases.
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